Diphenatol is an antidiarrheal and antispasmodic formulation typically containing diphenoxylate and atropine. Diphenoxylate works by slowing intestinal movement, while atropine is added in small amounts to discourage misuse due to its unpleasant side effects at high doses. It is used to manage moderate to severe non-infectious diarrhea and is considered more potent than loperamide in some cases.